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Cingal®: A unique combination viscosupplement for osteoarthritis knee pain relief

What is Cingal®?

A single injection that provides the quick pain relief of a corticosteroid with the long-term pain relief of a viscosupplement

Cingal® is the only viscosupplement that combines a corticosteroid for fast pain relief with a viscosupplement, a clear gel-like substance containing hyaluronic acid, for sustained osteoarthritis knee pain relief.

Did you know?

A single intra-articular injection of Cingal® can provide rapid* osteoarthritis knee pain relief that’s felt as early as 1 week following the injection and that can last up to
6 months.

Corticosteroid
Fast-acting*
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viscosupplement
long-lasting
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cingal logo
Osteoarthritis
knee pain relief
How does it work?

Lubricant and anti-inflammatory properties working together

Over time, changes in the synovial fluid and degeneration of joint structures may lead to osteoarthritis knee pain.

Hyaluronic acid is a naturally occurring substance found in the synovial fluid of the knee joint. Viscosupplementation, or the injection of hyaluronic acid into the joint, is thought to lubricate the cartilage (much as oil lubricates an engine), thereby reducing pain for long-term relief with a delayed onset.

Corticosteroid (or cortisone) has anti-inflammatory properties and may be used to relieve pain by reducing swelling in the joint for short-term rapid relief.

Cingal® combines the lubricating effect of hyaluronic acid with the anti-inflammatory properties of a corticosteroid in a single injection.

How can it help?

Osteoarthritis and viscosupplementation

When you have osteoarthritis, there may not be enough natural hyaluronic acid in the joint, and the quality of that hyaluronic acid may be poorer than normal.

Cingal® is given in a single shot (injection) directly into the knee joint. The injection of Cingal® supplements (adds) hyaluronic acid into the knee joint. The corticosteroid contained in Cingal® quickly reduces inflammation to provide fast relief, while the hyaluronic acid cushions the knee joint to provide long-lasting relief.

Osteoarthritis knee joint

  1. Cartilage wears away: Over time, the bone surfaces may rub together.
  2. Synovial fluid becomes less healthy: The fluid becomes thinner and less elastic.
  3. Exposed bone
  4. Bone spurs
Is Cingal® right for me?

When to consider Cingal® for osteoarthritis knee pain relief

If oral painkillers and lifestyle changes such as exercising and losing weight are not providing you with adequate pain relief, Cingal® may be a good option to relieve your osteoarthritis knee pain.

Are you covered for Cingal®?

Access our private insurance coverage guide for reimbursement information on Cingal®.

Download the coverage guide

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Safety and side effects

  • Cingal® should be injected by a qualified physician or properly licensed practitioner.
  • Tell your healthcare professional if you have any known allergies before Cingal® is administered.
  • The safety and effectiveness of Cingal® have not been shown in pregnant or nursing women. You should tell your healthcare professional if you are pregnant or nursing.
  • Side effects are sometimes seen when Cingal® is injected into the knee joint. These can include pain, swelling, heat, rash, itching, bruising, and/or redness. You may also feel achy. The skin at the injection site may become thinner or change colour. You may experience facial flushing. These reactions are generally mild and do not last long.
  • If any of these symptoms or signs appear after you are given Cingal®, or if you have any other problems, you should call or visit your healthcare professional.

*Significant reduction in pain measures seen at Week 1 vs. saline (ITT p=0.008).